KMID : 0545120150250030353
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Journal of Microbiology and Biotechnology 2015 Volume.25 No. 3 p.353 ~ p.357
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Identification and Characterization of the Antifungal Substances of a Novel Streptomyces cavourensis NA4
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Hua-Qi Pan
Su-Ya Yu Chun-Feng Song Nan Wang Hui-Ming Hua Jiang-Chun Hu Shu-Jin Wang
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Abstract
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A new actinomycete strain NA4 was isolated from a deep-sea sediment collected from the South China Sea and showed promising antifungal activities against soilborne fungal pathogens. It was identified as Streptomyces cavourensis by morphological, physiological, and phylogenetic analyses based on its 16S rRNA gene sequence. The main antifungal components were isolated and identified from the fermentation culture as bafilomycins B1 and C1. These compounds exhibited significant antifungal activities and a broad antifungal spectrum. The results suggest that the Streptomyces cavourensis NA4 and bafilomycins B1 and C1 could be used as potential biocontrol agents for soilborne fungal diseases of plants.
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KEYWORD
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Streptomyces cavourensis, Bafilomycins, Antifungal activity, Fungicide, Marine actinomycete
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